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Stanford University School of Medicine blog

Metformin is physician-researcher Randall Stafford''s make some sense out of this mess of medications.

Most are given by mouth (oral), but injected insulin, which I''s experience with diabetes drugs, let''s experience, or the medications taken by you or a friend or family member, let’s start with the best medication, metformin.

Approved by the U.S. Food & Drug Administration in 1994, metformin is so critical to diabetes treatment that if you don’t tolerate it at first because of abdominal side effects, it’s worth trying again. Many of my patients who did not tolerate this drug at first did better when they started at low doses and then worked to increase the amount they could easily tolerate.

This is my first-line, go-to drug for diabetes, and I’m always surprised when I encounter a patient with Type 2 diabetes who’s not taking it. And, just to be clear, metformin is a generic and I have no financial interests related to its use. Interestingly, the origin of metformin can be traced back to a herbal remedy from French lilac that has been known since the Middle Ages. Here are just for 1 last update 2020/07/12 a few reasons metformin is so great:This is my first-line, go-to drug for diabetes, and I’m always surprised when I encounter a patient with Type 2 diabetes who’s not taking it. And, just to be clear, metformin is a generic and I have no financial interests related to its use. Interestingly, the origin of metformin can be traced back to a herbal remedy from French lilac that has been known since the Middle Ages. Here are just a few reasons metformin is so great:

  • It can help with weight loss, while nearly all other diabetes drugs cause weight gain.
  • Metformin reduces high blood sugar, but rarely lowers blood sugar to levels below normal. Most other drugs have the potential to cause life-threatening hypoglycemia (low blood sugar).
  • This drug can be continued even if it becomes necessary to start insulin.
  • It’s inexpensive, costing pharmacies as little as $0.06 per day of treatment.

home remedies for diabetes 🔥how to home remedies for diabetes for Metformin works by increasing the body’s response to insulin, effectively reversing the insulin resistance that causes Type 2 diabetes. Insulin resistance occurs when the body’s liver, muscle and fat cells require the 1 last update 2020/07/12 more and more insulin in the bloodstream to make them do their jobs.Metformin works by increasing the body’s response to insulin, effectively reversing the insulin resistance that causes Type 2 diabetes. Insulin resistance occurs when the body’s liver, muscle and fat cells require more and more insulin in the bloodstream to make them do their jobs.

It’s no surprise that it is widely used, with 72 percent of U.S. diabetes patients who take medications on metformin. It could be used even more often. If you have Type 2 diabetes, you need to be on metformin or have a good reason not to take it (like advanced kidney disease). If you’ve tried it and have had indigestion or other abdominal problems, it may be worth trying this wonder drug again.

There are six other major classes of blood-sugar lowering drugs used in Type 2 diabetes. While none of these drugs (except for insulin) are in the wonder drug category, quite often these medications are combined with metformin to get blood sugar back towards normal levels. We will review these next-best drugs in the next blog post.

Randall Stafford, MD, PhD, a professor of medicine and director of the Program on Prevention Outcomes and Practices, practices primary care internal medicine at Stanford. He is developing practical strategies to improve how physicians and consumers approach chronic disease treatment and prevention.

This is the sixth piece in the series, “Breaking Down Diabetes,” created for those with or at risk for diabetes as well as their family and friends. Previous blog posts addressed the pre-diabetes, diabetes complications, and goals for diabetes beyond blood sugar. Some data for this report come from IQVIA, Inc., previously known as QuintilesIMS. For additional information, please contact [email protected].

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home remedies for diabetes ☑how to home remedies for diabetes for This is the fifth in a series of blog posts, by Randall Stafford, MD, PhD discussing prediabetes and Type 2 diabetes.

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